#Evidencebasedmedicine

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#Evidencebasedmedicine Reel by @drmaryclaire (verified account) - Headed to your menopause or perimenopause appointment? Ask these 3 questions-and pay attention to the answers.
	1.	Are you willing to discuss hormone
299.3K
DR
@drmaryclaire
Headed to your menopause or perimenopause appointment? Ask these 3 questions—and pay attention to the answers. 1. Are you willing to discuss hormone therapy? → Red flag if they say no outright, dismiss your symptoms, or bring up outdated fear-mongering about risk. 2. What percentage of your patients are using hormone therapy? → Red flag if they say “almost none”—that likely means they’re not offering it, not that no one needs it. → Red flag if they say “100%”—that suggests a one-size-fits-all approach, which isn’t good medicine either. 3. Which types of hormone therapy do you offer? → Red flag if the only option is pellet therapy. That’s an ethical red flag. Pellets are not FDA-approved, often deliver supraphysiologic doses, and can be expensive and irreversible for months. There are multiple safe, effective, and customizable options—like transdermal estrogen, micronized progesterone, and more. Your care should never be limited to one method. You’re not being difficult. You’re being informed. And that’s powerful. #menopause #perimenopause #drmaryclaire #thenewmenopause #hrt #womenshealth #menopauseadvocate #selfadvocacy #evidencebasedmedicine
#Evidencebasedmedicine Reel by @outrohealth - FREE Taper Resources in Bio!
Cam LaBar @coldplungecam shares with Dr. Mark Horowitz the existential challenge many people face when coming off antidep
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OU
@outrohealth
FREE Taper Resources in Bio! Cam LaBar @coldplungecam shares with Dr. Mark Horowitz the existential challenge many people face when coming off antidepressants after years or decades on them: How much of who you are is shaped by the medication? The often ignored reality is that when your brain has adapted to a drug after many years of use, the process of rediscovering your unmedicated baseline involves both biological recalibration and genuine self-discovery. The path forward requires safe, gradual tapering with expert support. That’s why Outro combines hyperbolic tapering, continuous monitoring, and clinician guidance to help you navigate both the physical and existential aspects of coming off medication. Learn more at outro.com or via the link in our profile. #AntidepressantWithdrawal #DeprescribingAwareness #EvidenceBasedMedicine #MentalHealthAwareness
#Evidencebasedmedicine Reel by @theangry_doc (verified account) - INSTAGRAM DOCTORS EXPOSED: Why Your ₹900 'Premium' B12 Supplement Is Medical Theater - PubMed Speaks 💉🔬

Your "sublingual methylcobalamin" costs 3x
195.1K
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@theangry_doc
INSTAGRAM DOCTORS EXPOSED: Why Your ₹900 ‘Premium’ B12 Supplement Is Medical Theater - PubMed Speaks 💉🔬 Your “sublingual methylcobalamin” costs 3x more. Science says it works the SAME as ₹300 oral cyanocobalamin. 🚨 MYTH-BUSTING FACTS: ✅ 2025 Meta-Analysis (6,098 patients): NO difference between oral, sublingual, IM routes (p=0.270) ✅ Sublingual “better absorption”? BUSTED. At 1000mcg, passive diffusion works equally for all routes. ✅ Methylcobalamin “superior”? Only for diabetic neuropathy. For general deficiency, cyanocobalamin = cheaper + equally effective. 🎯 THE GRAY ZONE NOBODY TALKS ABOUT: B12 = 200-400 pg/mL? Lab says “normal” but you feel exhausted? 26% have FUNCTIONAL DEFICIENCY - missed by serum B12, caught by MMA test. Landmark study: 644 cases missed by B12 alone, detected by MMA (Methylmalonic Acid). 💊 EVIDENCE-BASED PROTOCOL: If B12 200-400 + symptoms: 1️⃣ Test MMA (₹2,500) + Homocysteine 2️⃣ If MMA >260 nmol/L → Treat with: - Cyanocobalamin 1000mcg daily - Folate 400-800mcg (if Hcy high) - B6 25-50mg (if Hcy high) 3️⃣ Retest MMA after 6-8 weeks Cost Reality: - Sublingual “premium”: ₹900/month - Oral cyanocobalamin: ₹300/month - Same result. Save ₹7,200/year. “MMA dekho. Homocysteine samjho. Patient treat karo, lab range nahi.” 📚 Sources: 16-study meta-analysis (Frontiers Pharmacology 2025), 13-study network analysis (Irish J Med Science 2024), Clinical Chemistry (2011), Am J Hematology (1990) ⚠️ DISCLAIMER: Educational content only. Not medical advice. Consult your healthcare provider before changing supplements or medications. Individual cases require personalized assessment. Save this. Share this. Stop wasting money on marketing myths. #VitaminB12 #MedicalMythBusting #EvidenceBasedMedicine #FunctionalDeficiency #MMATest
#Evidencebasedmedicine Reel by @shrutipatelmd (verified account) - There's been a lot of talk online about "turbo cancers" supposedly caused by the COVID vaccine, but that claim just doesn't hold up to the data.

📊 C
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@shrutipatelmd
There’s been a lot of talk online about “turbo cancers” supposedly caused by the COVID vaccine, but that claim just doesn’t hold up to the data. 📊 Cancer rates in young people have been rising, but this trend started decades before COVID ever existed. 🧬 Large population studies have found no increase in cancer diagnoses after vaccination. 💉 Vaccines don’t cause cancer AND IF anything, some vaccines prevent it (like HPV and hepatitis B). Science evolves, but the evidence here is clear: the COVID vaccine didn’t cause cancer. #CancerMyths #Oncology #CovidVaccineFacts #CancerPrevention #EvidenceBasedMedicine #EarlyOnsetCancer #CancerAwareness
#Evidencebasedmedicine Reel by @dr.samrudhi_bhanushali - Dry eyes aren't just "tired eyes."
It's a tear film disorder involving inflammation + tear instability.

🔬 Evidence shows prolonged screen time ↓ bli
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@dr.samrudhi_bhanushali
Dry eyes aren’t just “tired eyes.” It’s a tear film disorder involving inflammation + tear instability. 🔬 Evidence shows prolonged screen time ↓ blink rate → ↑ tear evaporation. 💧 Artificial tears help, but treating the cause matters more. #DryEyeDisease #EvidenceBasedMedicine #OcularSurface #doctorexplains
#Evidencebasedmedicine Reel by @dr.gluckswellnesscenter - 🚫 "Estradiol has no vascular benefit"? That's a MYTH.
Let's break it down with real science. 📚

💡 17-beta estradiol isn't just a hormone, it's a va
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@dr.gluckswellnesscenter
🚫 “Estradiol has no vascular benefit”? That’s a MYTH. Let’s break it down with real science. 📚 💡 17-beta estradiol isn’t just a hormone, it’s a vascular ally. Studies show it improves endothelial function, boosts nitric oxide, reduces vasoconstrictors like endothelin-1, and slows arterial aging. ⁠ 🧬 DOPS Trial (Schierbeck et al., BMJ 2012) showed that 10 years of estradiol reduced cardiovascular events and mortality in healthy postmenopausal women. ⁠ 🫀 ELITE Trial (Hodis et al., NEJM 2016) found that women who began estradiol early had less carotid artery thickening, a key marker of atherosclerosis. ⁠ 🔬 These aren’t fringe studies, they’re randomized, controlled, and peer-reviewed. ⁠ ❤️ Estradiol is not a cure for late-stage vascular disease. But saying it has no benefit ignores decades of real data. ⁠ #HormoneHealth #Estradiol #MetabolicHealth #HeartHealth #EvidenceBasedMedicine
#Evidencebasedmedicine Reel by @drgagovicgastroenterology (verified account) - • Vitamin A (retinol) - Chronic high intake (>10,000 IU/day) has been linked to reduced bone density and increased hip fracture risk.
PMID: 12213943
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@drgagovicgastroenterology
• Vitamin A (retinol) — Chronic high intake (>10,000 IU/day) has been linked to reduced bone density and increased hip fracture risk. PMID: 12213943 • Vitamin E — Higher doses (≥400 IU/day) associated with a small increase in bleeding (hemorrhagic) stroke risk. PMID: 20647268 • Vitamin B6 (pyridoxine) — Long-term high doses (commonly >100 mg/day) can cause sensory neuropathy and nerve damage. PMID: 2985233 • Beta-carotene (supplements) — High-dose supplementation increased lung cancer risk in smokers in major trials. PMID: 7504143 (ATBC) PMID: 8625198 (CARET) • Vitamin C — Higher supplemental intake (>1,000 mg/day) associated with increased kidney stone risk in some individuals. PMID: 23783537 More is not always better. Discuss long-term supplementation with your physician. #SupplementSafety #VitaminRisks #EvidenceBasedMedicine #PreventiveHealth #MedicalFacts
#Evidencebasedmedicine Reel by @lintaandayra (verified account) - Important update about autism treatment! 🚨 Stem cell therapy is NOT a proven treatment for autism. In fact, it's currently in the experimental phase,
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@lintaandayra
Important update about autism treatment! 🚨 Stem cell therapy is NOT a proven treatment for autism. In fact, it’s currently in the experimental phase, and there’s no conclusive evidence to support its effectiveness for autism. Many countries are banning or restricting its use for this purpose due to safety concerns and lack of scientific backing. Recently, India banned stem cell therapy for autism, and Pakistan’s Punjab Health Care Commission has issued warnings against centres offering it as a treatment. Don’t fall prey to false claims! If you’re seeking autism treatment, consult reputable healthcare professionals and focus on evidence-based therapies like behavioural and educational interventions. Let’s prioritize science and safety over unproven treatments! 💡 #AutismAwareness #StemCellTherapy #EvidenceBasedMedicine
#Evidencebasedmedicine Reel by @adeadamsonmd - A new large study in JAMA Network Open estimates that 72-94% of thyroid cancers diagnosed from 1991-2019 were likely overdiagnosed, meaning they were
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AD
@adeadamsonmd
A new large study in JAMA Network Open estimates that 72–94% of thyroid cancers diagnosed from 1991–2019 were likely overdiagnosed, meaning they were biologically indolent tumors that would not have led to death. This is a huge problem. Companies that market total body MRIs are just going to exacerbate this problem. And society will pay for it. #Overdiagnosis #ThyroidCancer #EvidenceBasedMedicine #CancerScreening #StayMoisturized
#Evidencebasedmedicine Reel by @vickichanmd - Maybe providing evidenced based care for the needy and marginalized isn't for you… 🤔

#doctorlife #premedlife #evidencebasedmedicine
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@vickichanmd
Maybe providing evidenced based care for the needy and marginalized isn’t for you… 🤔 #doctorlife #premedlife #evidencebasedmedicine
#Evidencebasedmedicine Reel by @agewellwithdrsteph (verified account) - Peptides are everywhere right now and the FDA just removed several from its restricted Category 2 list, meaning clinicians may now be able to compound
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AG
@agewellwithdrsteph
Peptides are everywhere right now and the FDA just removed several from its restricted Category 2 list, meaning clinicians may now be able to compound some of them, despite limited human safety and efficacy data. Follow me for my Peptide Science Series where I break down what’s actually known, what’s hype, and what’s still unknown. #Peptides #EvidenceBasedMedicine #Wellness #MedED #doctorsofinstagram
#Evidencebasedmedicine Reel by @doctoramiirah (verified account) - Eczema is not automatically caused by food - and fear-based marketing without evidence hurts families. This is one example of a page, but there are so
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DO
@doctoramiirah
Eczema is not automatically caused by food — and fear-based marketing without evidence hurts families. This is one example of a page, but there are so many out there where the evidence is not clear. And unfortunately, by not reading the fine print, you may be sold information that isn’t accurate. If you’re selling a course- or info - show the data. Show the trials. Show the guidelines. Otherwise we’re just amplifying misinformation. As medical professionals, it’s our job to protect parents from shame, confusion, and expensive promises that aren’t science. Let’s debunk with evidence. Always. 💛 #EczemaFacts #AtopicDermatitis #EvidenceBasedMedicine #PediatricAllergist #Dermatology

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