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BIResearchers at Eon Systems PBC have demonstrated a simulation where a digital fly body is controlled by a brain model built from real biological wiring. The brain model, published in Nature by Philip Shiu and colleagues, contains 125,000+ neurons and about 50 million synapses derived from the FlyWire map of the fruit fly brain.
By connecting this model to the NeuroMechFly body in a physics engine, sensory signals can enter the brain simulation and produce movement in the virtual body. This creates a full perception-to-action loop, allowing behaviors like walking and grooming to emerge from the brain’s neural circuits.
Source
The First Multi-Behavior Brain Upload “ published by Dr. Alex Wissner-Gross (alexwg on X)
DOI: 10.1038/s41592-024-02497-y
DOI: 10.1038/s41586-025-09029-4
DOI: 10.1038/s41586-024-07763-9
(For educational purposes only)
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