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BIOne of the most fascinating process in biology.
DNA replication is the biological process by which a cell makes an exact copy of its DNA before cell division. It's essential for growth, repair, and reproduction in all living organisms.
Key Steps in DNA Replication
1. Initiation
- Begins at specific sites called origins of replication.
- Helicase enzyme unwinds the double helix, forming a replication bubble with two replication forks.
- Single-strand binding proteins (SSBs) stabilize the unwound strands.
2. Primer Synthesis
- Primase lays down short RNA primers on each strand to provide a starting point for DNA synthesis.
3. Elongation
- DNA polymerase III adds new nucleotides.
- One strand (the leading strand) is synthesized continuously.
- The other (the lagging strand) is synthesized in short fragments called Okazaki fragments, which are later joined by DNA ligase.
4. Termination
- Once the entire DNA molecule is copied, enzymes remove the RNA primers and replace them with DNA.
- DNA ligase seals any gaps, completing the replication process.
📹 by yourgenome (yt)
#molecularbiology #molecularmedicine #cellmolecularbiology #microbiology
Direction of replication is...
@biologyscienc
![#Dna Replication Process Reel by @dr.popo__ (verified account) - [DNA Replication Process]
1. Close-up of the DNA Double Helix
2. Helicase Unwinding the DNA Double Helix
3. Primer Synthesis and Start of DNA Replicat](https://image.pictame.com/img/496613106_719644763929485_3362751791786661136_n.jpg?hash=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)