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BIOne of the most fascinating process in biology.
DNA replication is the biological process by which a cell makes an exact copy of its DNA before cell division. It's essential for growth, repair, and reproduction in all living organisms.
Key Steps in DNA Replication
1. Initiation
- Begins at specific sites called origins of replication.
- Helicase enzyme unwinds the double helix, forming a replication bubble with two replication forks.
- Single-strand binding proteins (SSBs) stabilize the unwound strands.
2. Primer Synthesis
- Primase lays down short RNA primers on each strand to provide a starting point for DNA synthesis.
3. Elongation
- DNA polymerase III adds new nucleotides.
- One strand (the leading strand) is synthesized continuously.
- The other (the lagging strand) is synthesized in short fragments called Okazaki fragments, which are later joined by DNA ligase.
4. Termination
- Once the entire DNA molecule is copied, enzymes remove the RNA primers and replace them with DNA.
- DNA ligase seals any gaps, completing the replication process.
📹 by yourgenome (yt)
#molecularbiology #molecularmedicine #cellmolecularbiology #microbiology
Direction of replication is...
@biologyscienc
![#Replication Dna Reel by @dr.popo__ (verified account) - [DNA Replication Process]
1. Close-up of the DNA Double Helix
2. Helicase Unwinding the DNA Double Helix
3. Primer Synthesis and Start of DNA Replicat](https://image.pictame.com/img/496613106_719644763929485_3362751791786661136_n.jpg?hash=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)
